ABSTRACT
Objective: to compare the ventilatory effects of the three-way laryngeal mask airway [TLMA] and tracheal tube [TT] on hemodynamics, respiratory function, and stress responses in a canine model during bronchoalveolar lavage [BAL]
Study Design: experimental study
Place and Duration of Study: the 303rd Hospital of the Chinese People's Liberation Army in May 2013
Methodology: sixteen dogs were divided into two groups. MAP, SpO[2] and HR were recorded before anesthesia [T[0]], immediately before intubation [T[1]], during intubation [T[2]], at 3 [T[3]] and 10 [T4] minutes after mechanical ventilation, at 10 [T[5]], 20 [T[6]], and 30 [T[7]] minutes during the course of BAL, during extubation [T[8]], and 3 minutes after extubation [T[9]]. Tidal volume, peak inspiratory airway pressure, and expiratory CO[2] pressure were recorded at time points T[2], T[5], T[6], T[7], and T[8]. Stress responses variables, including epinephrine and norepinephrine levels, were examined at time points T[0], T[2], T[3], T[5], T[8], and T[9]
Results: BAL was successfully completed in all animals. In comparison to the TT, the TLMA was capable of maintaining hemodynamic stability and ventilation [p < 0.05], and producing less stress responses [p < 0.05]
Conclusion: in a canine model, ventilation with the TLMA was better than the TT during BAL in terms of maintaining effective ventilation and stable hemodynamics, and producing less stress responses